Research Center for Translational Medicine
East Hospital
No. 150 Jimo Road
Shanghai 200120
China

WANG Ping, Ph.D,

Professor and Director

Department of Central Laboratory, 

Shanghai Tenth People's Hospital of Tongji University

School of Life Sciences and Technology

Tongji University

Shanghai, 200092 China

 

Wang Ping received his B.S. from Fudan University in 1997, and his Ph.D. in Molecular Cell Biology from the Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences in 2002.  He completed his postdoctoral training at the University of Minnesota, University of Connecticut Health Center, and Yale University from 2003 to 2008.  He was appointed as Professor in the College of Life Science, East China Normal University in 2008 and joined Tongji University in 2014.  His group focuses on the principal enzymatic components of the ubiquitin system - ubiquitin ligases and de-ubiquitylases - in cancer, inflammation and stem cells. His group also works on the identification of small molecules targeting the ubiquitin modification system.

 

Selected publications:

  1.  Deng L, Jiang C, Chen L, Jin J, Wei J, Zhao L, Chen M, Pan W, Xu Y, Chu H, Wang X, Ge X, Li D, Liao L, Liu M, Li L, and Wang P. The Ubiquitination of RagA GTPase by RNF152 negatively regulates mTORC1 activation. Mol. Cell 58:804-18 (2015).
  2.  Li R, Wei J, Jiang C, Liu D, Deng L, Zhang K, and Wang P. Akt sumoylation regulates cell proliferation and tumorigenesis. Cancer Res. 73:5742-53 (2013).
  3.  Xu W, Wang P, Petri B, Zhang Y, Tang W, Sun L, Kress H, Mann T, Shi Y, Kubes P, and Wu D. Integrin-induced Pip5k1c kinase polarization regulates neutrophil polarization, directionality, and in vivo infiltration. Immunity 33:340-50 (2010).
  4.  Liu N, Li H, Li S, Shen M, Xiao N, Chen Y, Wang Y, Wang W, Wang R, Wang Q, Sun J, and Wang P. The Fbw7/Human Cdc4 tumor suppressor targets proproliferative factor Klf5 for ubiquitination and degradation through multiple phosphodegron motifs. J. Biol. Chem. 285:18858-67 (2010).
  5.  Wang R, Wang Y, Liu N, Ren C, Jiang C, Zhang K, Yu S, Chen Y, Tang H, Deng Q, Fu C, Wang Y, Li R, Liu M, Pan W, and Wang P. Fbw7 Regulates Endothelial Functions by Targeting Klf2 for Ubiquitination and Degradation. Cell Res. 23:803-19 (2013).

 

Home Institution Website: http://life.tongji.edu.cn/Show.aspx?info_id=2307&info_lb=298&flag=98
E mail: pwangecnu@163.com